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11-13-2012, 11:04 PM
Hank Chinaski
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Originally Posted by Plan The Parade View Post
In order to "cure" Down Syndrome, wouldn't virtually every cell in the person's body have to be replaced?

Or is it just a certain type of cell that would have to be replaced, then the other cells would follow suit?
The trisomy (extra 21st chromosome) leads to largely irreversible effects during development of the fetus, so this isn't a possibility once a child with Down Syndrome is born. I think if you were talking about a "cure" for Down Syndrome that would remove the trisomy so that all cells would follow suit, it would have to target the totipotent or possibly multipotent cells at the very beginning of development.

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