Manning is a nice QB to have as your starter, McNabb, eh. Hes good for a backup, but really no need for 3 QBs. Tebow, dump him and play the waiver wire for a RB or WR.
WRs are weak. Smith is real nice, but Rice has injury questions now and the rest is very weak. Get rid of D. Williams and see if guys like Mike Williams (TB), Louis Murphy, Laurent Robinson, Massaquoi or Doucet are available. Any one of them is a better one to have.
RBs are excellent. This is your strongest position. No need to do anything there, but I would play around with some trade scenarios. Outside of your 3 RBs, you have no depth at all there. You need at least 1 more to have. In your case, I would look at trading one your weaker WRs for a bottom tier RB or possibly even trying to trade Turner for a 2 lesser RBs. Benson and Moreno is a solid combo, but if you trade Turner, you would be able to get a combo like Pierre Thomas-CJ. Spiller or something like that and that would round your RBs out even better. You definitely need at least 1 more RB on your team.
When your starting TE is Witten, you are fine. I would maybe check the waiver wire for another backup TE like a Fasano, Aaron Hernandez, Heap, or Scaife. All would be better than Cook.
K and DEF is fine. I liked CHI D as a sleeper this year with Peppers there.
Yeah I was a little surprised that people weren't higher on Malcom Floyd and then I grabbed Laurent Robinson with my 17th pick. Sure, he's a Ram but he's #1 on the depth chart now and somebody has to catch the ball.......
I think the WR depth is thin this year, so if you can get a guy that is up in the depth chart because of another players injury, then that's a good move. Same goes for Berrian with Sydney Rice being out.