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Calico cats may help the obese

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02-18-2014, 06:03 PM
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LadyStanley
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Calico cats may help the obese

http://news.discovery.com/animals/pe...mkcpgn=rssnws1

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Elizabeth Smith of the University of California San Francisco and her colleagues explain that calico cats have an orange fur color gene on one of their X chromosomes and a black fur color gene on the other, so that the random silencing of one of the X's in each cell creates their distinctive patchwork coats.

"Uncovering how only one X chromosome is inactivated will help explain the whole process of epigenetic control, meaning the way changes in gene activity can be inherited without changing the DNA code," Smith said in a press release. "It can help answer other questions such as if and how traits like obesity can be passed down through generations.

The ultimate goal then is to figure out how many different kinds of genes can be turned on or off without altering the underlying DNA sequence.
Perhaps my next cat should be a calico?

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02-18-2014, 11:08 PM
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Fugu
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Calico cats cannot become overweight.

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02-18-2014, 11:11 PM
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Quote:
Originally Posted by Fugu View Post
Calico cats cannot become overweight.
Welcome to my lair. I mean... Forum.

That seems like a bit of a jump by these researchers from fur colour to obesity.

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02-18-2014, 11:26 PM
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Quote:
Originally Posted by Hurt View Post
Welcome to my lair. I mean... Forum.

That seems like a bit of a jump by these researchers from fur colour to obesity.
My name is still up in the forum intro sticky!

It is a bit of jump. I was thinking of dissecting this statement:
"Uncovering how only one X chromosome is inactivated will help explain the whole process of epigenetic control, meaning the way changes in gene activity can be inherited without changing the DNA code," Smith said in a press release. "It can help answer other questions such as if and how traits like obesity can be passed down through generations.”

Is there only one process of epigenetic control, and if these processes are in fact heritable? The entire area of post-translational modification to gene expression is so complex that the mind boggles. What was learned from the Human Genome Project was that we actually did not have enough genes to explain all the variability seen in humans (the product of all that DNA). So obviously a heck of a lot of snipping and turning and off of genes at various stages of development was going on. How that's controlled and the timing of it is really quite fascinating, and will take many more decades to 'decode'.

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02-18-2014, 11:27 PM
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Both humans and cats are social creatures, and the interactions provide positive reinforcement. That alone creates significant benefits to pet owners. There's plenty of literature of the benefits of pet ownership.

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02-18-2014, 11:28 PM
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Both humans and cats are social creatures, and the interactions provide positive reinforcement. That alone creates significant benefits to pet owners. There's plenty of literature of the benefits of pet ownership.

Dog people will tell you that cats are not social creatures.


Tell Richer's Ghost that cats >>>>> dogs.

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02-19-2014, 07:37 AM
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Personally obesity tendancy would not be the first thing I would try to wipe out if I were a genetic engineer trying to render alleles inactive, but that's just me.

There's a few nasty condition out there caused by a dominant defective genes that I woul get to first, just saying.

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02-19-2014, 11:12 AM
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Quote:
Originally Posted by Fugu View Post
Calico cats cannot become overweight.
I've never met a Calico that wasn't overweight lmao.

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02-25-2014, 02:15 PM
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Quote:
Originally Posted by Fugu View Post
Dog people will tell you that cats are not social creatures.


Tell Richer's Ghost that cats >>>>> dogs.
Cats are lousy pets!!

Dog's are productive members of society who can have a real job, whereas cats are maybe good for killing a fly or mice.

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02-25-2014, 03:57 PM
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Cats are lousy pets!!

Dog's are productive members of society who can have a real job, whereas cats are maybe good for killing a fly or mice.

Protecting your home from rodent infestation IS a job. Best part is that the cat feeds itself in this case, is small and doesn't take up much room.

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02-25-2014, 05:27 PM
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Canadiens Ghost
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Protecting your home from rodent infestation IS a job. Best part is that the cat feeds itself in this case, is small and doesn't take up much room.
... and isn't emotionally dependent to the point of wanting to die if you leave them alone for more than 5 minutes.

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