Is it a hole in the middle of the palm material or the stitching? I had a glove where the stitching kept coming out on the thumb and had to sew it back together...looked like hell but worked. Otherwise you could try some moleskin from the drugstore as a patch, kind of like the palm saver stuff.
I had the same hole in the glove happen to me. Thankfully it led me to buying new gloves that fit properly. But I did realize that it probably occurred from cleaning my blade of snow on the bench. Now I always use my bare hand to clean my blade.