Flyers/Leafs was a great series last year and both teams have only gotten better assuming that they're healthy. Though the games have been one sided lately, I'd expect it to be very hard hitting, nasty, and pretty close with the flyers winning in 6. Also, Toronto/Ottawa would be a great series and one that i'm hoping happens because the only east team I see taking out Ottawa is Toronto.
One of the reasons not mentioned, and probably not well known outside of Nashville is that there is a large number of Detroit transplants in the areas outside the city who moved here when auto plants for Saturn and Nissan opened up.
In earlier years, Wings fans outnumbered us in our building and it was joked we were Joe Lewis South. In later years, we've been able to get some of the red out, so to speak.
All in all, its made for some pretty memorable games just on the crowd's enthusiam alone. I can only image what a playoff series would bring.